USC-OGP 2-DE database Two-dimensional polyacrylamide gel electrophoresis database

USC-OGP 2-DE database  Search by                Maps             Select Remote Interfaces [All Interfaces] SWISS-2DPAGE World-2DPAGE Portal World-2DPAGE Repository Exclude local DBs has only effect if a remote interface is selected

Searching in 'USC-OGP 2-DE database' for entry matching: ACTH_HUMAN USC-OGP 2-DE database:  ACTH_HUMAN ACTH_HUMAN General information about the entry View entry in simple text format Entry name ACTH_HUMAN Primary accession number P63267 Secondary accession number(s) P12718 integrated into USC-OGP 2-DE database on  January 17, 2017 (release 1) 2D Annotations were last modified on January 17, 2017 (version 1) General Annotations were last modified on  April 5, 2017 (version 2) Name and origin of the protein Description RecName: Full=Actin, gamma-enteric smooth muscle; AltName: Full=Alpha-actin-3; AltName: Full=Gamma-2-actin; AltName: Full=Smooth muscle gamma-actin; Flags: Precursor;. Gene name Name=ACTG2 Synonyms=ACTA3, ACTL3, ACTSG Annotated species Homo sapiens (Human) [TaxID: 9606] Taxonomy Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. References [1]   2D GEL CHARACTERIZATION Author 1., Author 2. Submitted (Mar-2011) to Current 2D PAGE maps for identified proteins How to interpret a protein PLATELET_4-5 {PLATELET 4-5} Homo sapiens (Human)   map experimental info   PLATELET_4-5 MAP LOCATIONS: SPOT OGP-0082: pI=4.83; Mw=45828 SPOT OGP-0084: pI=4.66; Mw=45387 Cross-references UniProtKB/Swiss-Prot P63267; ACTH_HUMAN. 2D PAGE maps for identified proteins How to interpret a protein map You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw. Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly. Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed. External data extracted from UniProtKB/Swiss-Prot Extracted from UniProtKB/Swiss-Prot, release: 0.0 Entry name ACTH_HUMAN Primary accession number P63267 Secondary accession number(s) B2R7E7 B4E315 D6W5H8 E9PG30 P12718 Q504R1 Q6FI22 Sequence was last modified on  October 11, 2004 (version 1) Annotations were last modified on  March 15, 2017 (version 125) Name and origin of the protein Description RecName: Full=Actin, gamma-enteric smooth muscle; AltName: Full=Alpha-actin-3; AltName: Full=Gamma-2-actin; AltName: Full=Smooth muscle gamma-actin; Flags: Precursor; Gene name Name=ACTG2 Synonyms=ACTA3, ACTL3, ACTSG Encoded on Name=ACTG2; Synonyms=ACTA3, ACTL3, ACTSG Keywords Acetylation; Alternative splicing; ATP-binding; Complete proteome; Cytoplasm; Cytoskeleton; Disease mutation; Isopeptide bond; Muscle protein; Nucleotide-binding; Oxidation; Reference proteome. Copyright Copyrighted by the UniProt Consortium, see http://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License Cross-references EMBL X16940; CAA34814.1; -; mRNA EMBL D00654; BAA00546.1; -; Genomic_DNA EMBL AK304523; BAG65327.1; -; mRNA EMBL AK312955; BAG35794.1; -; mRNA EMBL CR536515; CAG38753.1; -; mRNA EMBL CR541794; CAG46593.1; -; mRNA EMBL AC073046; AAX88909.1; -; Genomic_DNA EMBL CH471053; EAW99713.1; -; Genomic_DNA EMBL BC012617; AAH12617.1; -; mRNA EMBL BC094877; AAH94877.1; -; mRNA CCDS CCDS1930.1; -. [P63267-1]; . CCDS CCDS56124.1; -. [P63267-2]; . PIR A40261; A40261; . RefSeq NP_001186822.1; NM_001199893.1. [P63267-2]; . RefSeq NP_001606.1; NM_001615.3. [P63267-1]; . UniGene Hs.516105; -; . ProteinModelPortal P63267; -; . SMR P63267; -; . BioGrid 106587; 17; . IntAct P63267; 10; . MINT MINT-256943; -; . STRING 9606.ENSP00000295137; -; . iPTMnet P63267; -; . PhosphoSitePlus P63267; -; . SwissPalm P63267; -; . BioMuta ACTG2; -; . DMDM 54036679; -; . OGP P12718; -; . MaxQB P63267; -; . PaxDb P63267; -; . PeptideAtlas P63267; -; . PRIDE P63267; -; . DNASU 72; -; . Ensembl ENST00000345517; ENSP00000295137; ENSG00000163017. [P63267-1]; . Ensembl ENST00000409624; ENSP00000386857; ENSG00000163017. [P63267-1]; . Ensembl ENST00000409731; ENSP00000386929; ENSG00000163017. [P63267-2]; . GeneID 72; -; . KEGG hsa:72; -; . UCSC uc002sjw.4; human. [P63267-1]; . CTD 72; -; . DisGeNET 72; -; . GeneCards ACTG2; -; . HGNC HGNC:145; ACTG2; . HPA HPA041264; -; . HPA HPA041271; -; . MalaCards ACTG2; -; . MIM 102545; gene; . MIM 155310; phenotype; . neXtProt NX_P63267; -; . OpenTargets ENSG00000163017; -; . Orphanet 2604; Familial visceral myopathy; . Orphanet 2241; Megacystis-microcolon-intestinal hypoperistalsis syndrome; . Orphanet 104077; Myopathic intestinal pseudoobstruction; . PharmGKB PA24469; -; . eggNOG KOG0676; Eukaryota; . eggNOG COG5277; LUCA; . GeneTree ENSGT00760000118957; -; . HOGENOM HOG000233340; -; . HOVERGEN HBG003771; -; . InParanoid P63267; -; . KO K12315; -; . OMA QXEREIV; -; . OrthoDB EOG091G08LD; -; . PhylomeDB P63267; -; . TreeFam TF354237; -; . Reactome R-HSA-445355; Smooth Muscle Contraction; . SignaLink P63267; -; . ChiTaRS ACTG2; human; . GeneWiki ACTG2; -; . GenomeRNAi 72; -; . PMAP-CutDB P63267; -; . PRO PR:P63267; -; . Proteomes UP000005640; Chromosome 2; . Bgee ENSG00000163017; -; . CleanEx HS_ACTG2; -; . ExpressionAtlas P63267; baseline and differential; . Genevisible P63267; HS; . GO GO:0072562; C:blood microparticle; IDA:UniProtKB; . GO GO:0044297; C:cell body; ISS:AgBase; . GO GO:0071944; C:cell periphery; IEA:Ensembl; . GO GO:0005737; C:cytoplasm; ISS:AgBase; . GO GO:0005829; C:cytosol; TAS:Reactome; . GO GO:0070062; C:extracellular exosome; IDA:UniProtKB; . GO GO:0005615; C:extracellular space; IDA:UniProtKB; . GO GO:0030175; C:filopodium; ISS:AgBase; . GO GO:0030027; C:lamellipodium; ISS:AgBase; . GO GO:0032982; C:myosin filament; ISS:AgBase; . GO GO:0005524; F:ATP binding; IEA:UniProtKB-KW; . GO GO:0090131; P:mesenchyme migration; ISS:AgBase; . GO GO:0006936; P:muscle contraction; TAS:Reactome; . GO GO:0010628; P:positive regulation of gene expression; ISS:AgBase; . InterPro IPR004000; Actin; . InterPro IPR020902; Actin/actin-like_CS; . InterPro IPR004001; Actin_CS; . PANTHER PTHR11937; PTHR11937; 1; . Pfam PF00022; Actin; 1; . PRINTS PR00190; ACTIN; . SMART SM00268; ACTIN; 1; . PROSITE PS00406; ACTINS_1; 1; . PROSITE PS00432; ACTINS_2; 1; . PROSITE PS01132; ACTINS_ACT_LIKE; 1; .

Gateways to other related servers

• The World-2DPAGE Constellation - Entry point to the world-wide 2-DPAGE resources.
• World-2DPAGE Repository - A public repository for gel-based proteomics data linked to protein identification published in the literature.
• World-2DPAGE Portal - A dynamic portal to query simultaneously world-wide gel-based proteomics databases.
• SWISS-2DPAGE - The Geneva Two-dimensional polyacrylamide gel electrophoresis database.
• ExPASy - The resources web server of the Swiss Institute of Bioinformatics

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